@gaetan @janvladimirmostert (a little late for the discussion)
I do use Colemak. Before ever knowing Colemak was a think I tried switching to Dvorak a few times but actually gave up, it felt like the learning curve was way too steep, mainly because of keyboard shortcuts.
On Colemak only a few shortcuts were moved as the keys Q, W, A, Z, X, C, V all stay on the same place, so copying, pasting, closing tabs and apps didn't change at all.