Nope. Client (user agent or proxy acting on its behalf) makes connection to what it thinks is a server. E.g.

<http://foo.bar.com/index.html>

But it happens to be reverse proxy, like nginx. Which forwards connection to actual http server in DMZ. E.g. to

service-bar.intranet:8765/fooApplication/index.html

The first connection is described as

origin

, the second as

local

. E.g. when you want to make external link and send it by email, you need to know how your application looks from the outer-net. That’s normally passed by proxy to application in additional headers.